Optibrium provides software for compound design, optimisation and data analysis.
StarDrop, an integrated suite of software, enables you to deliver optimally balance, successful compounds, fast.
Successful compounds require a balance of many different properties: potency, ADME, safety… StarDrop guides you through this ‘multi-parameter optimisation’ challenge to rapidly explore design strategies and target compounds with the best chance of success, saving you time and resources by synthesising and testing fewer compounds.
StarDrop’s unique approach to multi-parameter optimisation integrates data from many sources to prioritise compounds for your project’s specific goals. This takes into account the inherent uncertainty in discovery data to identify when compounds can be confidently distinguished and avoid missing valuable opportunities.
StarDrop’s core features can be extended with optional plug-in modules that provide comprehensive capabilities for compound optimisation, including: Predictive models for ADME properties, P450 metabolism and toxicity; automatic QSAR model building; 3D structure-activity relationships; and de novo design to stimulate the search for new optimisation strategies.
As an enterprise platform StarDrop can connect seamlessly with your models, informatics methods and databases. By providing user-friendly access to these resources, it makes project management quicker and simpler.
User-friendly querying of databases enables you to create, share and run structured queries, returning results directly into StarDrop ready for visualisation and analysis. Connection to additional data sources like CDD Vault, BIOVIA’s ScienceCloud or Certara’s D360 are available as free extensions. Search third-party commercial databases for screening compounds or select building blocks for synthesis and retrieve biological data from public databases, such as ChEMBL and PubChem.
StarDrop enables expertly prepared 3D docking and alignment models to be linked with data visualisation, 2D SAR analyses and predictive models in a single, elegant environment and is compatible with software from all the major computational chemistry providers.
Optibrium sponsor of the PLA2018 edition will be available for further information during the event.
To learn more visit: www.optibrium.com/stardrop